Acetyl Hexapeptide-3 (Argireline) (200mg)
- Size: 5mg or 10mg per vial (contact for custom sizes)
- Content: Acetyl Hexapeptide-3
- Form: Lyophilized powder
- Purity: ≥99%
- SKU: AH3-5MG or AH3-10MG
Acetyl Hexapeptide-3 (also known as Argireline) is a synthetic hexapeptide widely utilized in laboratory research for its potential effects on neurotransmitter release and facial muscle contraction. As a botulinum toxin-like peptide, it is studied for its ability to modulate SNAP-25 protein interactions, which may influence wrinkle formation and skin smoothness in preclinical dermal models. Researchers explore Acetyl Hexapeptide-3 in the context of topical peptide formulations, anti-aging mechanisms, and extracellular matrix interactions.
At AetherPeakPeptides.com, Acetyl Hexapeptide-3 is supplied in high-purity lyophilized form for advanced dermatological and cosmetic science investigations. This stable hexapeptide continues to be a key subject in studies focused on non-invasive approaches to skin appearance and muscle relaxation signaling.
Chemical and Structural Specifications
| Property | Specification |
|---|---|
| Sequence | Ac-Glu-Glu-Met-Gln-Arg-Arg-NH₂ |
| Molecular Formula | C₃₄H₆₀N₁₄O₁₁S |
| Molecular Weight | Approximately 889.0 g/mol |
| CAS Number | 616204-22-9 |
| Purity | ≥99% (HPLC / MS verified) |
Acetyl Hexapeptide-3 features an N-terminal acetylation that enhances stability in research applications.
Mechanism of Action in Research Models
In laboratory settings, Acetyl Hexapeptide-3 is investigated for its ability to interfere with the formation of the SNARE complex by competing with SNAP-25. This modulation may reduce neurotransmitter release at neuromuscular junctions, leading to decreased muscle contraction in experimental dermal models. Researchers also study its penetration properties and effects on collagen expression in skin fibroblast cultures.
Key Research Applications
Acetyl Hexapeptide-3 is commonly employed in studies examining:
- Facial muscle contraction and wrinkle formation models
- Topical peptide delivery and skin penetration
- Anti-aging and photoaging mechanisms
- Extracellular matrix remodeling in dermal tissues
- Formulation development for cosmetic peptides
Why Researchers Choose Acetyl Hexapeptide-3 at AetherPeakPeptides.com
Our Acetyl Hexapeptide-3 is manufactured to exacting laboratory standards with detailed analytical verification. The lyophilized format provides excellent stability for formulation and penetration studies. Multiple vial sizes support both preliminary screening and larger-scale dermal research projects.
Handling and Storage Guidelines
- Reconstitution: Use sterile water or appropriate buffer. Swirl gently to dissolve.
- Storage: Lyophilized vials at -20°C. Reconstituted solution refrigerated at 2–8°C and used within recommended periods.
- Best Practices: Maintain aseptic techniques during all laboratory procedures.
For Research Use Only Acetyl Hexapeptide-3 is sold exclusively for laboratory and scientific research purposes. It is not intended for human consumption, therapeutic applications, or veterinary use. Researchers must comply with all applicable regulations.
Research specifications
| Sequence | — |
| Molecular formula | — |
| Molecular weight | — |
| Purity | ≥ 99% |
| Appearance | White lyophilised powder |
| Reconstitution | Bacteriostatic water or sterile water for injection |
| Storage | Lyophilised: 2–8°C. Reconstituted: -20°C. |
| Stability | 24 months lyophilised / 6 weeks reconstituted (frozen) |
| Research use | For laboratory and in-vitro research use only |
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Lab results & certificate of analysis
Every batch shipped from AetherPeak is independently tested by a certified third-party laboratory. The certificate of analysis (COA) for this product verifies purity, identity, and the absence of contaminants before it leaves our facility.
What our COA covers
- HPLC purity analysis (minimum threshold: 98%)
- Mass spectrometry identity confirmation
- Heavy metal and microbial contamination screening
- Moisture content and residual solvent testing
Shipping & storage information
| Packaging | Plain, unbranded outer packaging — no product names visible |
| Cold chain | Temperature-sensitive peptides shipped with ice packs or dry ice where required |
| Processing time | Orders processed and dispatched within 24 hours of payment confirmation |
| Domestic shipping | 2–5 business days tracked |
| International shipping | 5–14 business days depending on destination and customs |
| Tracking | Full tracking number provided via email at dispatch |
| Returns | Accepted within 30 days for unopened items — see refund policy |
Storage recommendations
- Lyophilised (freeze-dried): store at 2–8°C, away from light and moisture
- After reconstitution: store at -20°C, use within 4–6 weeks
- Avoid repeated freeze-thaw cycles once reconstituted
- Keep away from direct UV light at all times
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