TB-500 (Thymosin Beta 4) (5mg / 10mg)
- Size: 5mg or 10mg per vial
- Content: TB-500 (Thymosin Beta-4)
- Form: Lyophilized powder
- Purity: ≥99%
- SKU: TB500-5MG or TB500-10MG
Product Description for TB-500 (Thymosin Beta 4)
TB-500 (Thymosin Beta-4) is a synthetic peptide widely utilized in laboratory research for its roles in tissue repair, cell migration, and actin regulation. As a fragment of the naturally occurring Thymosin Beta-4 protein, it is studied for its ability to promote wound healing, angiogenesis, and connective tissue remodeling in preclinical models. Researchers frequently investigate TB-500 in the context of musculoskeletal recovery, inflammation modulation, and regenerative biology.
TB-500 is supplied in high-purity lyophilized vials for advanced scientific investigations. This peptide remains a cornerstone in studies exploring cellular motility and systemic tissue repair mechanisms.
Chemical and Structural Specifications
| Property | Specification |
|---|---|
| Sequence | Ac-LKKTETQ (active fragment) |
| Molecular Formula | C₃₈H₆₈N₁₀O₁₄ |
| Molecular Weight | Approximately 889.02 g/mol |
| CAS Number | 885340-08-9 |
| Purity | ≥99% (HPLC / MS verified) |
TB-500 corresponds to the key actin-binding domain of the larger Thymosin Beta-4 protein, offering researchers a focused tool for cytoskeletal studies.
Mechanism of Action in Research Models
TB-500 primarily functions through high-affinity binding to G-actin monomers, modulating the polymerization into F-actin filaments. This regulation supports cell migration, cytoskeletal reorganization, and angiogenesis. In laboratory models, it is explored for its contributions to wound contraction, fibroblast activation, and tissue remodeling processes.
Key Research Applications
TB-500 is commonly employed in studies examining:
- Muscle, tendon, and ligament repair models
- Wound healing and scar reduction
- Angiogenesis and vascular regeneration
- Systemic tissue recovery and inflammation
- Actin dynamics in cellular motility
Why Researchers Choose TB-500 at Aether Peak Peptides
Our TB-500 is produced to stringent laboratory standards with detailed batch verification. The lyophilized format ensures long-term stability, ideal for multi-phase injury and recovery research protocols. Consistent quality and reliable documentation support reproducible experimental results.
Handling and Storage Guidelines
- Reconstitution: Use bacteriostatic water. Swirl gently to dissolve.
- Storage: Lyophilized vials at -20°C. Reconstituted solution refrigerated at 2–8°C and used within recommended periods.
- Best Practices: Maintain aseptic laboratory techniques during all procedures.
For Research Use Only TB-500 is sold exclusively for laboratory and scientific research purposes. It is not intended for human consumption, therapeutic applications, or veterinary use. Researchers must comply with all applicable regulations.
Research specifications
| Sequence | — |
| Molecular formula | — |
| Molecular weight | — |
| Purity | ≥ 99% |
| Appearance | White lyophilised powder |
| Reconstitution | Bacteriostatic water or sterile water for injection |
| Storage | Lyophilised: 2–8°C. Reconstituted: -20°C. |
| Stability | 24 months lyophilised / 6 weeks reconstituted (frozen) |
| Research use | For laboratory and in-vitro research use only |
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Lab results & certificate of analysis
Every batch shipped from AetherPeak is independently tested by a certified third-party laboratory. The certificate of analysis (COA) for this product verifies purity, identity, and the absence of contaminants before it leaves our facility.
What our COA covers
- HPLC purity analysis (minimum threshold: 98%)
- Mass spectrometry identity confirmation
- Heavy metal and microbial contamination screening
- Moisture content and residual solvent testing
Shipping & storage information
| Packaging | Plain, unbranded outer packaging — no product names visible |
| Cold chain | Temperature-sensitive peptides shipped with ice packs or dry ice where required |
| Processing time | Orders processed and dispatched within 24 hours of payment confirmation |
| Domestic shipping | 2–5 business days tracked |
| International shipping | 5–14 business days depending on destination and customs |
| Tracking | Full tracking number provided via email at dispatch |
| Returns | Accepted within 30 days for unopened items — see refund policy |
Storage recommendations
- Lyophilised (freeze-dried): store at 2–8°C, away from light and moisture
- After reconstitution: store at -20°C, use within 4–6 weeks
- Avoid repeated freeze-thaw cycles once reconstituted
- Keep away from direct UV light at all times
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